If you have designed a grid in Excel with the flag /Parameters in the grid name, this grid won't display as a spreadsheet but as a parameter editor. Please follow the Setup parameters editor for more information for implementing the parameter editor.
Just answer the questions set up in Excel and click on Save parameters to save the results just as if you had edited cells.
You can dynamically add columns to the parameters set by clicking on the buttons at the right of the parameter set name.

Do not forget to launch simulations or enable live mode to see changes after you save in the model.